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Late morfofunctional alterations of the Sertoli cell caused by doxorubicin administered to prepubertal rats
BACKGROUND: Doxorubicin is a potent chemotherapeutic drug used against a variety of cancers. It acts through interaction with polymerases and topoisomerase II and free radical production. Doxorubicin activity is not specific to cancer cells and can also damage healthy cells, especially those undergo...
Autores principales: | Brilhante, Otávio, Okada, Fatima K, Sasso-Cerri, Estela, Stumpp, Taiza, Miraglia, Sandra M |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3502149/ https://www.ncbi.nlm.nih.gov/pubmed/22967030 http://dx.doi.org/10.1186/1477-7827-10-79 |
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