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Anti-plasmodial action of de novo-designed, cationic, lysine-branched, amphipathic, helical peptides
BACKGROUND: A lack of vaccine and rampant drug resistance demands new anti-malarials. METHODS: In vitro blood stage anti-plasmodial properties of several de novo-designed, chemically synthesized, cationic, amphipathic, helical, antibiotic peptides were examined against Plasmodium falciparum using SY...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3502156/ https://www.ncbi.nlm.nih.gov/pubmed/22853877 http://dx.doi.org/10.1186/1475-2875-11-256 |