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Anti-plasmodial action of de novo-designed, cationic, lysine-branched, amphipathic, helical peptides

BACKGROUND: A lack of vaccine and rampant drug resistance demands new anti-malarials. METHODS: In vitro blood stage anti-plasmodial properties of several de novo-designed, chemically synthesized, cationic, amphipathic, helical, antibiotic peptides were examined against Plasmodium falciparum using SY...

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Detalles Bibliográficos
Autores principales: Kaushik, Naveen K, Sharma, Jyotsna, Sahal, Dinkar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3502156/
https://www.ncbi.nlm.nih.gov/pubmed/22853877
http://dx.doi.org/10.1186/1475-2875-11-256