Tissue-specific control of CFTR endocytosis by Dab2: Cargo recruitment as a therapeutic target

Clathrin-mediated endocytosis dynamically regulates cell membrane abundance of CFTR and plays an essential role in CFTR-dependent Cl(-) conductance in fluid-transporting epithelia. It requires two closely related, but distinct processes: assembly of the clathrin coat and recruitment of cargo protein...

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Detalles Bibliográficos
Autores principales: Madden, Dean R., Swiatecka-Urban, Agnieszka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2012
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3502210/
https://www.ncbi.nlm.nih.gov/pubmed/23181163
http://dx.doi.org/10.4161/cib.21375

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3502210/
https://www.ncbi.nlm.nih.gov/pubmed/23181163
http://dx.doi.org/10.4161/cib.21375

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