Cargando…
Tissue-specific control of CFTR endocytosis by Dab2: Cargo recruitment as a therapeutic target
Clathrin-mediated endocytosis dynamically regulates cell membrane abundance of CFTR and plays an essential role in CFTR-dependent Cl(-) conductance in fluid-transporting epithelia. It requires two closely related, but distinct processes: assembly of the clathrin coat and recruitment of cargo protein...
| Autores principales: | , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Landes Bioscience
2012
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3502210/ https://www.ncbi.nlm.nih.gov/pubmed/23181163 http://dx.doi.org/10.4161/cib.21375 |