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Molecular mechanism of the “feedback loop” model of carcinogenesis

It is commonly accepted that cancer is a genetic disease. The current prevailing theory of carcinogenesis is the somatic mutation theory of carcinogenesis and metastasis (SMT). This theory postulates that mutations in epithelial cells lead to uncontrolled proliferation of tumor cells in a cell-auton...

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Detalles Bibliográficos
Autores principales: Rückert, Felix, Sticht, Carsten, Niedergethmann, Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3502218/
https://www.ncbi.nlm.nih.gov/pubmed/23739683
http://dx.doi.org/10.4161/cib.21177