Identification of Small Molecule Inhibitors of PTPσ through an Integrative Virtual and Biochemical Approach

PTPσ is a dual-domain receptor type protein tyrosine phosphatase (PTP) with physiologically important functions which render this enzyme an attractive biological target. Specifically, loss of PTPσ has been shown to elicit a number of cellular phenotypes including enhanced nerve regeneration followin...

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Detalles Bibliográficos
Autores principales: Martin, Katie R., Narang, Pooja, Xu, Yong, Kauffman, Audra L., Petit, Joachim, Xu, H. Eric, Meurice, Nathalie, MacKeigan, Jeffrey P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3502291/
https://www.ncbi.nlm.nih.gov/pubmed/23185579
http://dx.doi.org/10.1371/journal.pone.0050217

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3502291/
https://www.ncbi.nlm.nih.gov/pubmed/23185579
http://dx.doi.org/10.1371/journal.pone.0050217

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