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Identification of Small Molecule Inhibitors of PTPσ through an Integrative Virtual and Biochemical Approach
PTPσ is a dual-domain receptor type protein tyrosine phosphatase (PTP) with physiologically important functions which render this enzyme an attractive biological target. Specifically, loss of PTPσ has been shown to elicit a number of cellular phenotypes including enhanced nerve regeneration followin...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3502291/ https://www.ncbi.nlm.nih.gov/pubmed/23185579 http://dx.doi.org/10.1371/journal.pone.0050217 |