Zerumbone suppresses IKKα, Akt, and FOXO1 activation, resulting in apoptosis of GBM 8401 cells

BACKGROUND: Zerumbone, a sesquiterpene compound isolated from subtropical ginger, Zingiber zerumbet Smith, has been documented to exert antitumoral and anti- inflammatory activities. In this study, we demonstrate that zerumbone induces apoptosis in human glioblastoma multiforme (GBM8401) cells and i...

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Detalles Bibliográficos
Autores principales: Weng, Hsing-Yu, Hsu, Ming-Jen, Wang, Ching-Chung, Chen, Bing-Chang, Hong, Chuang-Ye, Chen, Mei-Chieh, Chiu, Wen-Ta, Lin, Chien-Huang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3502293/
https://www.ncbi.nlm.nih.gov/pubmed/23035900
http://dx.doi.org/10.1186/1423-0127-19-86

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3502293/
https://www.ncbi.nlm.nih.gov/pubmed/23035900
http://dx.doi.org/10.1186/1423-0127-19-86

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