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The tumor suppressor gene RBM5 inhibits lung adenocarcinoma cell growth and induces apoptosis

BACKGROUND: The loss of tumor suppressor gene (TSG) function is a critical step in the pathogenesis of human lung cancer. RBM5 (RNA-binding motif protein 5, also named H37/LUCA-15) gene from chromosome 3p21.3 demonstrated tumor suppressor activity. However, the role of RBM5 played in the occurrence...

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Detalles Bibliográficos
Autores principales: Shao, Chen, Zhao, Lijing, Wang, Ke, Xu, Wei, Zhang, Jie, Yang, Baoxue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3502321/
https://www.ncbi.nlm.nih.gov/pubmed/22866867
http://dx.doi.org/10.1186/1477-7819-10-160