Biochemical Characterization of Diverse Stat5b-Binding Enhancers That Mediate Growth Hormone-Activated Insulin-Like Growth Factor-I Gene Transcription

Many of the biological effects of growth hormone (GH) are mediated by insulin-like growth factor I (IGF-I), a 70-amino acid secreted peptide whose gene expression is rapidly induced by GH via the Stat5b transcription factor. We previously identified multiple evolutionarily conserved GH-activated chr...

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Detalles Bibliográficos
Autores principales: Varco-Merth, Ben, Mirza, Kasim, Alzhanov, Damir T., Chia, Dennis J., Rotwein, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3502335/
https://www.ncbi.nlm.nih.gov/pubmed/23185594
http://dx.doi.org/10.1371/journal.pone.0050278

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3502335/
https://www.ncbi.nlm.nih.gov/pubmed/23185594
http://dx.doi.org/10.1371/journal.pone.0050278

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