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Expression of Paracoccidioides brasiliensis AMY1 in a Histoplasma capsulatum amy1 Mutant, Relates an α-(1,4)-Amylase to Cell Wall α-(1,3)-Glucan Synthesis

In the cell walls of the pathogenic yeast phases of Paracoccidioides brasiliensis, Blastomyces dermatitidis and Histoplasma capsulatum, the outer α-(1,3)-glucan layer behaves as a virulence factor. In H. capsulatum, an α-(1,4)-amylase gene (AMY1) is essential for the synthesis of this polysaccharide...

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Detalles Bibliográficos
Autores principales: Camacho, Emma, Sepulveda, Victoria E., Goldman, William E., San-Blas, Gioconda, Niño-Vega, Gustavo A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3502345/
https://www.ncbi.nlm.nih.gov/pubmed/23185578
http://dx.doi.org/10.1371/journal.pone.0050201