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DNA Abasic Site-Selective Enhancement of Sanguinarine Fluorescence with a Large Emission Shift

Small molecules that can specifically bind to a DNA abasic site (AP site) have received much attention due to their importance in DNA lesion identification, drug discovery, and sensor design. Herein, the AP site binding behavior of sanguinarine (SG), a natural alkaloid, was investigated. In aqueous...

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Detalles Bibliográficos
Autores principales: Wu, Fei, Sun, Yanwei, Shao, Yong, Xu, Shujuan, Liu, Guiying, Peng, Jian, Liu, Lingling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3502418/
https://www.ncbi.nlm.nih.gov/pubmed/23185252
http://dx.doi.org/10.1371/journal.pone.0048251