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DNA Abasic Site-Selective Enhancement of Sanguinarine Fluorescence with a Large Emission Shift
Small molecules that can specifically bind to a DNA abasic site (AP site) have received much attention due to their importance in DNA lesion identification, drug discovery, and sensor design. Herein, the AP site binding behavior of sanguinarine (SG), a natural alkaloid, was investigated. In aqueous...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3502418/ https://www.ncbi.nlm.nih.gov/pubmed/23185252 http://dx.doi.org/10.1371/journal.pone.0048251 |