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Mechanical strain promotes osteoblast ECM formation and improves its osteoinductive potential

BACKGROUND: The extracellular matrix (ECM) provides a supportive microenvironment for cells, which is suitable as a tissue engineering scaffold. Mechanical stimulus plays a significant role in the fate of osteoblast, suggesting that it regulates ECM formation. Therefore, we investigated the influenc...

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Detalles Bibliográficos
Autores principales: Guo, Yong, Zhang, Chun-qiu, Zeng, Qiang-cheng, Li, Rui-xin, Liu, Lu, Hao, Qin-xin, Shi, Cai-hong, Zhang, Xi-zheng, Yan, Yu-xian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3502495/
https://www.ncbi.nlm.nih.gov/pubmed/23098360
http://dx.doi.org/10.1186/1475-925X-11-80