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Identification of nephropathy candidate genes by comparing sclerosis-prone and sclerosis-resistant mouse strain kidney transcriptomes

BACKGROUND: The genetic architecture responsible for chronic kidney disease (CKD) remains incompletely described. The Oligosyndactyly (Os) mouse models focal and segmental glomerulosclerosis (FSGS), which is associated with reduced nephron number caused by the Os mutation. The Os mutation leads to F...

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Detalles Bibliográficos
Autores principales: El-Meanawy, Ashraf, Schelling, Jeffery R, Iyengar, Sudha K, Hayden, Patrick, Barathan, Shrinath, Goddard, Katrina, Pozuelo, Fatima, Elashi, Essam, Nair, Viji, Kretzler, Matthias, Sedor, John R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3502501/
https://www.ncbi.nlm.nih.gov/pubmed/22813067
http://dx.doi.org/10.1186/1471-2369-13-61