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The H-factor as a novel quality metric for homology modeling

BACKGROUND: Drug discovery typically starts with the identification of a potential target that is then tested and validated either through high-throughput screening against a library of drug compounds or by rational drug design. When the putative target is a protein, the latter approach requires the...

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Detalles Bibliográficos
Autores principales: di Luccio, Eric, Koehl, Patrice
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3502507/
https://www.ncbi.nlm.nih.gov/pubmed/23121764
http://dx.doi.org/10.1186/2043-9113-2-18