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Inhibition of the Prokaryotic Pentameric Ligand-Gated Ion Channel ELIC by Divalent Cations

The modulation of pentameric ligand-gated ion channels (pLGICs) by divalent cations is believed to play an important role in their regulation in a physiological context. Ions such as calcium or zinc influence the activity of pLGIC neurotransmitter receptors by binding to their extracellular domain a...

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Detalles Bibliográficos
Autores principales: Zimmermann, Iwan, Marabelli, Alessandro, Bertozzi, Carlo, Sivilotti, Lucia G., Dutzler, Raimund
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3502511/
https://www.ncbi.nlm.nih.gov/pubmed/23185134
http://dx.doi.org/10.1371/journal.pbio.1001429