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GSK3beta-Mediated Drp1 Phosphorylation Induced Elongated Mitochondrial Morphology against Oxidative Stress

Multiple phosphorylation sites of Drp1 have been characterized for their functional importance. However, the functional consequence of GSK3beta-mediated phosphorylation of Drp1 remains unclear. In this report, we pinpointed 11 Serine/Threonine sites spanning from residue 634∼736 of the GED domain an...

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Detalles Bibliográficos
Autores principales: Chou, Chia-Hua, Lin, Ching-Chih, Yang, Ming-Chang, Wei, Chih-Chang, Liao, Huei-De, Lin, Run-Chin, Tu, Wen-Yu, Kao, Tsung-Chieh, Hsu, Ching-Mei, Cheng, Jiin-Tsuey, Chou, An-Kuo, Lee, Chu-I, Loh, Joon-Khim, Howng, Shen-Long, Hong, Yi-Ren
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3502545/
https://www.ncbi.nlm.nih.gov/pubmed/23185298
http://dx.doi.org/10.1371/journal.pone.0049112