Impact of pre-existing MSP1(42)-allele specific immunity on potency of an erythrocytic Plasmodium falciparum vaccine

BACKGROUND: MSP1 is the major surface protein on merozoites and a prime candidate for a blood stage malaria vaccine. Preclinical and seroepidemiological studies have implicated antibodies to MSP1 in protection against blood stage parasitaemia and/or reduced parasite densities, respectively. Malaria...

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Detalles Bibliográficos
Autores principales: Bergmann-Leitner, Elke S, Duncan, Elizabeth H, Mease, Ryan M, Angov, Evelina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3502560/
https://www.ncbi.nlm.nih.gov/pubmed/22958482
http://dx.doi.org/10.1186/1475-2875-11-315

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3502560/
https://www.ncbi.nlm.nih.gov/pubmed/22958482
http://dx.doi.org/10.1186/1475-2875-11-315

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