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Impact of pre-existing MSP1(42)-allele specific immunity on potency of an erythrocytic Plasmodium falciparum vaccine

BACKGROUND: MSP1 is the major surface protein on merozoites and a prime candidate for a blood stage malaria vaccine. Preclinical and seroepidemiological studies have implicated antibodies to MSP1 in protection against blood stage parasitaemia and/or reduced parasite densities, respectively. Malaria...

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Detalles Bibliográficos
Autores principales:	Bergmann-Leitner, Elke S, Duncan, Elizabeth H, Mease, Ryan M, Angov, Evelina
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3502560/ https://www.ncbi.nlm.nih.gov/pubmed/22958482 http://dx.doi.org/10.1186/1475-2875-11-315

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