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Implantation of undifferentiated and pre-differentiated human neural stem cells in the R6/2 transgenic mouse model of Huntington’s disease

BACKGROUND: Cell therapy is a potential therapeutic approach for several neurodegenetative disease, including Huntington Disease (HD). To evaluate the putative efficacy of cell therapy in HD, most studies have used excitotoxic animal models with only a few studies having been conducted in genetic an...

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Detalles Bibliográficos
Autores principales: El-Akabawy, Gehan, Rattray, Ivan, Johansson, Saga M, Gale, Richard, Bates, Gillian, Modo, Michel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3502570/
https://www.ncbi.nlm.nih.gov/pubmed/22876937
http://dx.doi.org/10.1186/1471-2202-13-97