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Use of inert gas jets to measure the forces required for mechanical gene transfection

BACKGROUND: Transferring genes and drugs into cells is central to how we now study, identify and treat diseases. Several non-viral gene therapy methods that rely on the mechanical disruption of the plasma membrane have been proposed, but the success of these methods has been limited due to a lack of...

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Detalles Bibliográficos
Autores principales: Chouinard-Pelletier, Guillaume, Leduc, Mathieu, Guay, David, Coulombe, Sylvain, Leask, Richard L, Jones, Elizabeth AV
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3502573/
https://www.ncbi.nlm.nih.gov/pubmed/22963645
http://dx.doi.org/10.1186/1475-925X-11-67