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Use of inert gas jets to measure the forces required for mechanical gene transfection
BACKGROUND: Transferring genes and drugs into cells is central to how we now study, identify and treat diseases. Several non-viral gene therapy methods that rely on the mechanical disruption of the plasma membrane have been proposed, but the success of these methods has been limited due to a lack of...
Autores principales: | Chouinard-Pelletier, Guillaume, Leduc, Mathieu, Guay, David, Coulombe, Sylvain, Leask, Richard L, Jones, Elizabeth AV |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3502573/ https://www.ncbi.nlm.nih.gov/pubmed/22963645 http://dx.doi.org/10.1186/1475-925X-11-67 |
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