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Bmi-1 promotes the aggressiveness of glioma via activating the NF-kappaB/MMP-9 signaling pathway

BACKGROUND: The prognosis of human glioma is poor, and the highly invasive nature of the disease represents a major impediment to current therapeutic modalities. The oncoprotein B-cell-specific Moloney murine leukemia virus integration site 1 protein (Bmi-1) has been linked to the development and pr...

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Detalles Bibliográficos
Autores principales: Jiang, Lili, Wu, Jueheng, Yang, Yi, Liu, Liping, Song, Libing, Li, Jun, Li, Mengfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3502583/
https://www.ncbi.nlm.nih.gov/pubmed/22967049
http://dx.doi.org/10.1186/1471-2407-12-406