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Combined exposure to Maneb and Paraquat alters transcriptional regulation of neurogenesis-related genes in mice models of Parkinson’s disease

BACKGROUND: Parkinson's disease (PD) is a multifactorial disease where environmental factors act on genetically predisposed individuals. Although only 5% of PD manifestations are associated with specific mutations, majority of PD cases are of idiopathic origin, where environment plays a promine...

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Detalles Bibliográficos
Autores principales: Desplats, Paula, Patel, Pruthul, Kosberg, Kori, Mante, Michael, Patrick, Christina, Rockenstein, Edward, Fujita, Masayo, Hashimoto, Makoto, Masliah, Eliezer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3502617/
https://www.ncbi.nlm.nih.gov/pubmed/23017109
http://dx.doi.org/10.1186/1750-1326-7-49