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Generation of anti-Notch antibodies and their application in blocking Notch signalling in neural stem cells
Notch signalling occurs via direct cell–cell interactions and plays an important role in linking the fates of neighbouring cells. There are four different mammalian Notch receptors that can be activated by five cell surface ligands. The ability to inhibit specific Notch receptors would help identify...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Academic Press
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3502869/ https://www.ncbi.nlm.nih.gov/pubmed/22842086 http://dx.doi.org/10.1016/j.ymeth.2012.07.008 |