Impact of the Interaction between 3′-UTR SNPs and microRNA on the Expression of Human Xenobiotic Metabolism Enzyme and Transporter Genes

Genetic variation in the expression of human xenobiotic metabolism enzymes and transporters (XMETs) leads to inter-individual variability in metabolism of therapeutic agents as well as differed susceptibility to various diseases. Recent expression quantitative traits loci (eQTL) mapping in a few hum...

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Detalles Bibliográficos
Autores principales: Wei, Rongrong, Yang, Fan, Urban, Thomas J., Li, Lang, Chalasani, Naga, Flockhart, David A., Liu, Wanqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2012
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3502871/
https://www.ncbi.nlm.nih.gov/pubmed/23181071
http://dx.doi.org/10.3389/fgene.2012.00248

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3502871/
https://www.ncbi.nlm.nih.gov/pubmed/23181071
http://dx.doi.org/10.3389/fgene.2012.00248

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