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Impact of the Interaction between 3′-UTR SNPs and microRNA on the Expression of Human Xenobiotic Metabolism Enzyme and Transporter Genes
Genetic variation in the expression of human xenobiotic metabolism enzymes and transporters (XMETs) leads to inter-individual variability in metabolism of therapeutic agents as well as differed susceptibility to various diseases. Recent expression quantitative traits loci (eQTL) mapping in a few hum...
Autores principales: | Wei, Rongrong, Yang, Fan, Urban, Thomas J., Li, Lang, Chalasani, Naga, Flockhart, David A., Liu, Wanqing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3502871/ https://www.ncbi.nlm.nih.gov/pubmed/23181071 http://dx.doi.org/10.3389/fgene.2012.00248 |
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