Identification of G-Quadruplex Inducers Usinga Simple, Inexpensiveand Rapid High Throughput Assay, and TheirInhibition of Human Telomerase

Telomeres are protein and DNA complexes located atchromosome ends. Telomeric DNA is composed of a double stranded region of repetitive DNA followed by single-stranded 3' extension of aG-rich sequence. Single-stranded G-rich sequencescan fold into G-quadruplex structures,and molecules that stabi...

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Detalles Bibliográficos
Autores principales: Sassano, Maria Florencia, Schlesinger, Alexander P, Jarstfer, Michael B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bentham Open 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3502892/
https://www.ncbi.nlm.nih.gov/pubmed/23173022
http://dx.doi.org/10.2174/1874104501206010020

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3502892/
https://www.ncbi.nlm.nih.gov/pubmed/23173022
http://dx.doi.org/10.2174/1874104501206010020

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