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Overexpressing the CCL2 chemokine in an epithelial ovarian cancer cell line results in latency of in vivo tumourigenicity

The frequent loss of heterozygosity of chromosome (Chr) 17 in epithelial ovarian cancer (EOC), particularly high-grade ovarian serous carcinomas (HGOSCs), has been attributed to the disruption of known tumour suppressor genes, such as TP53 (17p13), as well as other genes on this chromosome that alon...

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Detalles Bibliográficos
Autores principales: Wojnarowicz, P, Gambaro, K, de Ladurantaye, M, Quinn, M C J, Provencher, D, Mes-Masson, A-M, Tonin, P N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3503293/
https://www.ncbi.nlm.nih.gov/pubmed/23552840
http://dx.doi.org/10.1038/oncsis.2012.25