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A Novel Multi-Scale Modeling Approach to Infer Whole Genome Divergence
We propose a novel and simple approach to elucidate genomic patterns of divergence using principal component analysis (PCA). We applied this methodology to the metric space generated by M. musculus genome-wide SNPs. Distance profiles were computed between M. musculus and its closely related species,...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Libertas Academica
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3503470/ https://www.ncbi.nlm.nih.gov/pubmed/23189028 http://dx.doi.org/10.4137/EBO.S10194 |