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Cumulative clinical experience from a decade of use: imatinib as first-line treatment of chronic myeloid leukemia
Chronic myeloid leukemia (CML) is a malignant disease that originates in the bone marrow and is designated by the presence of the Philadelphia (Ph+) chromosome, a translocation between chromosomes 9 and 22. Targeted therapy against CML commenced with the development of small-molecule tyrosine kinase...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2012
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3503471/ https://www.ncbi.nlm.nih.gov/pubmed/23180974 http://dx.doi.org/10.2147/JBM.S29132 |