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Vectorial secretion of CTGF as a cell-type specific response to LPA and TGF-β in human tubular epithelial cells

BACKGROUND: Increased expression of the pro-fibrotic protein connective tissue growth factor (CTGF) has been detected in injured kidneys and elevated urinary levels of CTGF are discussed as prognostic marker of chronic kidney disease. There is evidence that epithelial cells lining the renal tubular...

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Detalles Bibliográficos
Autores principales: Zuehlke, Jonathan, Ebenau, Astrid, Krueger, Bettina, Goppelt-Struebe, Margarete
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3503564/
https://www.ncbi.nlm.nih.gov/pubmed/22938209
http://dx.doi.org/10.1186/1478-811X-10-25