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Vectorial secretion of CTGF as a cell-type specific response to LPA and TGF-β in human tubular epithelial cells
BACKGROUND: Increased expression of the pro-fibrotic protein connective tissue growth factor (CTGF) has been detected in injured kidneys and elevated urinary levels of CTGF are discussed as prognostic marker of chronic kidney disease. There is evidence that epithelial cells lining the renal tubular...
Autores principales: | Zuehlke, Jonathan, Ebenau, Astrid, Krueger, Bettina, Goppelt-Struebe, Margarete |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3503564/ https://www.ncbi.nlm.nih.gov/pubmed/22938209 http://dx.doi.org/10.1186/1478-811X-10-25 |
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