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Preliminary evidence of different selection pressures on cancer cells as compared to normal tissues
BACKGROUND: Cancer is characterized by both a high mutation rate as well as high rates of cell division and cell death. We postulate that these conditions will result in the eventual mutational inactivation of genes not essential to the survival of the cancer cell, while mutations in essential genes...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3503577/ https://www.ncbi.nlm.nih.gov/pubmed/23146329 http://dx.doi.org/10.1186/1742-4682-9-44 |