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Expression of DNA repair and replication genes in non-small cell lung cancer (NSCLC): a role for thymidylate synthetase (TYMS)

BACKGROUND: BRCA1 (B), ERCC1 (E), RRM1 (R) and TYMS (T) mRNA expression has been extensively studied with respect to NSCLC patient outcome upon various chemotherapy agents. However, these markers have not been introduced into clinical practice yet. One of the reasons seems to be lack of a standard a...

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Detalles Bibliográficos
Autores principales: Kotoula, Vassiliki, Krikelis, Dimitrios, Karavasilis, Vasilios, Koletsa, Triantafillia, Eleftheraki, Anastasia G, Televantou, Despina, Christodoulou, Christos, Dimoudis, Stefanos, Korantzis, Ippokratis, Pectasides, Dimitrios, Syrigos, Konstantinos N, Kosmidis, Paris A, Fountzilas, George
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3503623/
https://www.ncbi.nlm.nih.gov/pubmed/22866924
http://dx.doi.org/10.1186/1471-2407-12-342