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Omeprazole Blocks STAT6 Binding to the Eotaxin-3 Promoter in Eosinophilic Esophagitis Cells

BACKGROUND: Patients who have esophageal eosinophilia without gastroesophageal reflux disease (GERD) nevertheless can respond to proton pump inhibitors (PPIs), which can have anti-inflammatory actions independent of effects on gastric acid secretion. In esophageal cell cultures, omeprazole has been...

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Detalles Bibliográficos
Autores principales: Zhang, Xi, Cheng, Edaire, Huo, Xiaofang, Yu, Chunhua, Zhang, Qiuyang, Pham, Thai H., Wang, David H., Spechler, Stuart J., Souza, Rhonda F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3503709/
https://www.ncbi.nlm.nih.gov/pubmed/23185525
http://dx.doi.org/10.1371/journal.pone.0050037