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Omeprazole Blocks STAT6 Binding to the Eotaxin-3 Promoter in Eosinophilic Esophagitis Cells
BACKGROUND: Patients who have esophageal eosinophilia without gastroesophageal reflux disease (GERD) nevertheless can respond to proton pump inhibitors (PPIs), which can have anti-inflammatory actions independent of effects on gastric acid secretion. In esophageal cell cultures, omeprazole has been...
Autores principales: | Zhang, Xi, Cheng, Edaire, Huo, Xiaofang, Yu, Chunhua, Zhang, Qiuyang, Pham, Thai H., Wang, David H., Spechler, Stuart J., Souza, Rhonda F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3503709/ https://www.ncbi.nlm.nih.gov/pubmed/23185525 http://dx.doi.org/10.1371/journal.pone.0050037 |
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