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The CCL2/CCR2 Axis Enhances Vascular Cell Adhesion Molecule-1 Expression in Human Synovial Fibroblasts

BACKGROUND: Chemokine ligand 2 (CCL2), also known as monocyte chemoattractant protein-1 (MCP-1), belongs to the CC chemokine family that is associated with the disease status and outcomes of osteoarthritis (OA). Here, we investigated the intracellular signaling pathways involved in CCL2-induced vasc...

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Detalles Bibliográficos
Autores principales: Lin, Yu-Min, Hsu, Chin-Jung, Liao, Yuan-Ya, Chou, Ming-Chih, Tang, Chih-Hsin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3503714/
https://www.ncbi.nlm.nih.gov/pubmed/23185512
http://dx.doi.org/10.1371/journal.pone.0049999