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Transfusion of CXCR4-Primed Endothelial Progenitor Cells Reduces Cerebral Ischemic Damage and Promotes Repair in db/db Diabetic Mice

This study investigated the role of stromal cell-derived factor-1α (SDF-1α)/CXC chemokine receptor 4 (CXCR4) axis in brain and endothelial progenitor cells (EPCs), and explored the efficacy of CXCR4 primed EPCs in treating ischemic stroke in diabetes. The db/db diabetic and db/+ mice were used in th...

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Detalles Bibliográficos
Autores principales: Chen, Ji, Chen, Jianying, Chen, Shuzhen, Zhang, Cheng, Zhang, Liangqing, Xiao, Xiang, Das, Avik, Zhao, Yuhui, Yuan, Bin, Morris, Mariana, Zhao, Bin, Chen, Yanfang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3503762/
https://www.ncbi.nlm.nih.gov/pubmed/23185548
http://dx.doi.org/10.1371/journal.pone.0050105