Inducible HSP70 Antagonizes IL-1β Cytocidal Effects through Inhibiting NF-kB Activation via Destabilizing TAK1 in HeLa Cells

BACKGROUND: Despite several reports describing the HSP70-mediated cytoprotection against IL-1, the precise mechanism for this phenomenon remains to be determined. METHODS/PRINCIPAL FINDINGS: Here we used HeLa cells, a human epithelial carcinoma cell line, to evaluate the role of inducible HSP70 in r...

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Detalles Bibliográficos
Autores principales: Cao, Xiang, Yue, Ling, Song, JiYun, Wu, Qiuyue, Li, Na, Luo, Lan, Lan, Lei, Yin, Zhimin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3503766/
https://www.ncbi.nlm.nih.gov/pubmed/23185533
http://dx.doi.org/10.1371/journal.pone.0050059

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3503766/
https://www.ncbi.nlm.nih.gov/pubmed/23185533
http://dx.doi.org/10.1371/journal.pone.0050059

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