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An engineered diatom acting like a plasma cell secreting human IgG antibodies with high efficiency

BACKGROUND: Although there are many different expression systems for recombinant production of pharmaceutical proteins, many of these suffer from drawbacks such as yield, cost, complexity of purification, and possible contamination with human pathogens. Microalgae have enormous potential for diverse...

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Detalles Bibliográficos
Autores principales: Hempel, Franziska, Maier, Uwe G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3503769/
https://www.ncbi.nlm.nih.gov/pubmed/22970838
http://dx.doi.org/10.1186/1475-2859-11-126