Cargando…

miR-200c Targets a NF-κB Up-Regulated TrkB/NTF3 Autocrine Signaling Loop to Enhance Anoikis Sensitivity in Triple Negative Breast Cancer

Anoikis is apoptosis initiated upon cell detachment from the native extracellular matrix. Since survival upon detachment from basement membrane is required for metastasis, the ability to resist anoikis contributes to the metastatic potential of breast tumors. miR-200c, a potent repressor of epitheli...

Descripción completa

Detalles Bibliográficos
Autores principales: Howe, Erin N., Cochrane, Dawn R., Cittelly, Diana M., Richer, Jennifer K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3503774/
https://www.ncbi.nlm.nih.gov/pubmed/23185507
http://dx.doi.org/10.1371/journal.pone.0049987