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The effect of sulindac, a non-steroidal anti-inflammatory drug, attenuates inflammation and fibrosis in a mouse model of chronic pancreatitis

BACKGROUND: Chronic pancreatitis is characterized by progressive fibrosis, pain and loss of exocrine and endocrine functions. The long-standing chronic pancreatitis and its associated pancreatic fibrosis are the most common pathogenic events involved in human pancreatic carcinogenesis, but the thera...

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Detalles Bibliográficos
Autores principales: Bai, Han, Chen, Xiaokai, Zhang, Lin, Dou, Xiaoguang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3503779/
https://www.ncbi.nlm.nih.gov/pubmed/22920325
http://dx.doi.org/10.1186/1471-230X-12-115