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A Conserved C-Terminal Domain of the Aspergillus fumigatus Developmental Regulator MedA Is Required for Nuclear Localization, Adhesion and Virulence

MedA is a developmental regulator that is conserved in the genome of most filamentous fungi. In the pathogenic fungus Aspergillus fumigatus MedA regulates conidiogenesis, adherence to host cells, and pathogenicity. The mechanism by which MedA governs these phenotypes remains unknown. Although the nu...

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Detalles Bibliográficos
Autores principales: Al Abdallah, Qusai, Choe, Se-In, Campoli, Paolo, Baptista, Stefanie, Gravelat, Fabrice N., Lee, Mark J., Sheppard, Donald C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3503810/
https://www.ncbi.nlm.nih.gov/pubmed/23185496
http://dx.doi.org/10.1371/journal.pone.0049959