Expression levels of multidrug resistance-associated protein 4 (MRP4) in human leukemia and lymphoma cell lines, and the inhibitory effects of the MRP-specific inhibitor MK-571 on methotrexate distribution in rats

In the development of anti-blood cancer drugs, the chronic myelocytic leukemia (KU812), acute myelocytic leukemia (KG-1) and lymphoma (U937) cell lines are commonly used in preclinical pharmacology studies as human cancer xenograft models in mice. In the present study, mRNA expression levels of typi...

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Detalles Bibliográficos
Autores principales: TAKEUCHI, KENJI, SHIBATA, MASAKAZU, KASHIYAMA, EIJI, UMEHARA, KEN
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2012
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3503844/
https://www.ncbi.nlm.nih.gov/pubmed/23181130
http://dx.doi.org/10.3892/etm.2012.627

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3503844/
https://www.ncbi.nlm.nih.gov/pubmed/23181130
http://dx.doi.org/10.3892/etm.2012.627

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