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Construction of a novel vector expressing the fusion suicide gene yCDglyTK and hTERT-shRNA and its antitumor effects

This study aimed to construct a novel recombinant expression vector, pcDNA3.1(-)hTERT-shRNA/yCDglyTK. Its bioactivity and antitumor effects were investigated in the SGC7901 human gastric cancer cell line. Interfering RNA (RNAi) targeting human telomerase reverse transcriptase (hTERT) was applied to...

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Detalles Bibliográficos
Autores principales: LI, JIA, ZHANG, GUIYING, LIU, TING, GU, HUAN, YAN, LU, CHEN, BOLIN
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3503886/
https://www.ncbi.nlm.nih.gov/pubmed/23181115
http://dx.doi.org/10.3892/etm.2012.613