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Genetic Variant SCL2A2 Is Associated with Risk of Cardiovascular Disease – Assessing the Individual and Cumulative Effect of 46 Type 2 Diabetes Related Genetic Variants

AIM: To assess the individual and combined effect of 46 type 2 diabetes related risk alleles on incidence of a composite CVD endpoint. METHODS: Data from the first Danish MONICA study (N = 3523) and the Inter99 study (N = 6049) was used. Using Cox proportional hazard regression the individual effect...

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Detalles Bibliográficos
Autores principales: Borglykke, Anders, Grarup, Niels, Sparsø, Thomas, Linneberg, Allan, Fenger, Mogens, Jeppesen, Jørgen, Hansen, Torben, Pedersen, Oluf, Jørgensen, Torben
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3503928/
https://www.ncbi.nlm.nih.gov/pubmed/23185617
http://dx.doi.org/10.1371/journal.pone.0050418