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Human Monoclonal Antibodies against Highly Conserved HR1 and HR2 Domains of the SARS-CoV Spike Protein Are More Broadly Neutralizing

Immune sera from convalescent patients have been shown to be effective in the treatment of patients infected with Severe Acute Respiratory Syndrome Virus (SARS-CoV) making passive immune therapy with human monoclonal antibodies an attractive treatment strategy for SARS. Previously, using Xenomouse (...

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Detalles Bibliográficos
Autores principales: Elshabrawy, Hatem A., Coughlin, Melissa M., Baker, Susan C., Prabhakar, Bellur S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3503966/
https://www.ncbi.nlm.nih.gov/pubmed/23185609
http://dx.doi.org/10.1371/journal.pone.0050366