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In Vivo Imaging of Hierarchical Spatiotemporal Activation of Caspase-8 during Apoptosis
BACKGROUND: Activation of caspases is crucial for the execution of apoptosis. Although the caspase cascade associated with activation of the initiator caspase-8 (CASP8) has been investigated in molecular and biochemical detail, the dynamics of CASP8 activation are not fully understood. METHODOLOGY/P...
Autores principales: | , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3503975/ https://www.ncbi.nlm.nih.gov/pubmed/23185580 http://dx.doi.org/10.1371/journal.pone.0050218 |