In Vivo Imaging of Hierarchical Spatiotemporal Activation of Caspase-8 during Apoptosis

BACKGROUND: Activation of caspases is crucial for the execution of apoptosis. Although the caspase cascade associated with activation of the initiator caspase-8 (CASP8) has been investigated in molecular and biochemical detail, the dynamics of CASP8 activation are not fully understood. METHODOLOGY/P...

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Detalles Bibliográficos
Autores principales: Kominami, Katsuya, Nagai, Takeharu, Sawasaki, Tatsuya, Tsujimura, Yuki, Yashima, Kenta, Sunaga, Yasuhiro, Tsuchimochi, Masateru, Nishimura, Jun, Chiba, Kumiko, Nakabayashi, Jun, Koyamada, Koji, Endo, Yaeta, Yokota, Hideo, Miyawaki, Atsushi, Manabe, Noboru, Sakamaki, Kazuhiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3503975/
https://www.ncbi.nlm.nih.gov/pubmed/23185580
http://dx.doi.org/10.1371/journal.pone.0050218

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